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Dynamics of kinks activated in the genes ADRB2, NOS1 and IL-5
Computer Research and Modeling, 2012, v. 4, no. 2, pp. 391-399Views (last year): 1. Citations: 2 (RSCI).In this paper the method of concentrations is applied to the human genome. The dynamical characteristics of three different genes (ADRB2, NOS1, IL-5) with the established effect on bronchial asthma.
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Dynamical characteristics of DNA kinks and antikinks
Computer Research and Modeling, 2012, v. 4, no. 1, pp. 209-217Views (last year): 2. Citations: 7 (RSCI).In this article in the frameworks of the sine-Gordon mode we have calculated the dynamical characteristics of kinks and antikinks activated in the homogeneous polynucleotide chains each if them contains only one of the types of the bases: adenines, thymines, guanines or cytosines. We have obtained analytical formulas and constructed the graphs for the kink and antikink profiles and for their energy density in the 2D- and 3D-dimension. Mass of kinks and antikinks, their energy of rest and their size have been estimated. The trajectories of kink and antikink motion in the phase space have been calculated in the 2D- and 3D-dimension.
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International Interdisciplinary Conference "Mathematics. Computing. Education"