Результаты поиска по 'bioinformatics':
Найдено статей: 2
  1. Nikulin V.N.
    On the stochastic gradient descent matrix factorization in application to the supervised classification of microarrays
    Computer Research and Modeling, 2013, v. 5, no. 2, pp. 131-140

    Microarray datasets are highly dimensional, with a small number of collected samples in comparison to thousands of features. This poses a significant challenge that affects the interpretation, applicability and validation of the analytical results. Matrix factorizations have proven to be a useful method for describing data in terms of a small number of meta-features, which reduces noise, while still capturing the essential features of the data. Three novel and mutually relevant methods are presented in this paper: 1) gradient-based matrix factorization with two adaptive learning rates (in accordance with the number of factor matrices) and their automatic updates; 2) nonparametric criterion for the selection of the number of factors; and 3) nonnegative version of the gradient-based matrix factorization which doesn't require any extra computational costs in difference to the existing methods. We demonstrate effectiveness of the proposed methods to the supervised classification of gene expression data.

    Keywords: matrix factorization, unsupervised learning, number of factors, nonnegativity, bioinformatics, leaveone-out, classification.
    Citations: 4 (RSCI).
  2. Dzhoraev A.R.
    GPU-accelerated hybrid systems for high-performance computing in bio-informatics
    Computer Research and Modeling, 2010, v. 2, no. 2, pp. 163-167

    Modern GPUs are massively-parallel processors, offering substantial amount of computational power in energy-efficient package. We discuss the benefits of utilizing this computing power for modeling problems in bio-informatics, such as molecular dynamics, quantum chemistry and sequence analysis.

    Keywords: GPU, bioinformatics, molecular dynamics, quantum chemistry, sequence analysis.
    Views (last year): 2. Citations: 6 (RSCI).

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