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We suggested some approaches for solving image processing tasks in the decision support system (DSS) of the Center for Automated Recording of Administrative Offenses of the Road Traffic (CARAO). The main task of this system is to assist the operator in obtaining accurate information about the vehicle registration plate and the vehicle brand/model based on images obtained from the photo and video recording systems. We suggested the approach for vehicle registration plate recognition and brand/model classification on the images based on modern neural network models. LPRNet neural network model supplemented by Spatial Transformer Layer was used to recognize the vehicle registration plate. The ResNeXt-101-32x8d neural network model was used to classify for vehicle brand/model. We suggested the approach to construct the training set for the neural network of vehicle registration plate recognition. The approach is based on computer vision methods and machine learning algorithms. The SIFT algorithm was used to detect and describe local features on images with the vehicle registration plate. DBSCAN clustering was used to detect and delete outliers in such local features. The accuracy of vehicle registration plate recognition was 96% on the testing set. We suggested the approach to improve the efficiency of using the ResNeXt-101-32x8d model at additional training and classification stages. The approach is based on the new architecture of convolutional neural networks with “freezing” weight coefficients of convolutional layers, an additional convolutional layer for parallelizing the classification process, and a set of binary classifiers at the output. This approach significantly reduced the time of additional training of neural network when new vehicle brand/model classification was needed. The final accuracy of vehicle brand/model classification was 99% on the testing set. The proposed approaches were tested and implemented in the DSS of the CARAO of the Republic of Tatarstan.

The repressilator is the first genetic regulatory network in synthetic biology, which was artificially constructed in 2000. It is a closed network of three genetic elements $lacI$, $\lambda cI$ and $tetR$, which have a natural origin, but are not found in nature in such a combination. The promoter of each of the three genes controls the next cistron via the negative feedback, suppressing the expression of the neighboring gene. In our previous paper [Bratsun et al., 2018], we proposed a mathematical model of a delayed repressillator and studied its properties within the framework of a deterministic description. We assume that delay can be both natural, i.e. arises during the transcription / translation of genes due to the multistage nature of these processes, and artificial, i.e. specially to be introduced into the work of the regulatory network using gene engineering technologies. In this work, we apply the stochastic description of dynamic processes in a delayed repressilator, which is an important addition to deterministic analysis due to the small number of molecules involved in gene regulation. The stochastic study is carried out numerically using the Gillespie algorithm, which is modified for time delay systems. We present the description of the algorithm, its software implementation, and the results of benchmark simulations for a onegene delayed autorepressor. When studying the behavior of a repressilator, we show that a stochastic description in a number of cases gives new information about the behavior of a system, which does not reduce to deterministic dynamics even when averaged over a large number of realizations. We show that in the subcritical range of parameters, where deterministic analysis predicts the absolute stability of the system, quasi-regular oscillations may be excited due to the nonlinear interaction of noise and delay. Earlier, we have discovered within the framework of the deterministic description, that there exists a long-lived transient regime, which is represented in the phase space by a slow manifold. This mode reflects the process of long-term synchronization of protein pulsations in the work of the repressilator genes. In this work, we show that the transition to the cooperative mode of gene operation occurs a two order of magnitude faster, when the effect of the intrinsic noise is taken into account. We have obtained the probability distribution of moment when the phase trajectory leaves the slow manifold and have determined the most probable time for such a transition. The influence of the intrinsic noise of chemical reactions on the dynamic properties of the repressilator is discussed.

Numerical modeling of turbulent flows requires finding the balance between accuracy and computational efficiency. For example, DNS and LES models allow to obtain more accurate results, comparing to RANS models, but are more computationally expensive. Because of this, modern applied simulations are mostly performed with RANS models. But even RANS models can be computationally expensive for complex geometries or series simulations due to the necessity of resolving the boundary layer. Some methods, such as wall functions and near-wall domain decomposition, allow to significantly improve the speed of RANS simulations. However, they inevitably lose precision due to using a simplified model in the near-wall domain. To obtain a model that is both accurate and computationally efficient, it is possible to construct a surrogate model based on previously made simulations using the precise model.

In this paper, an operator is constructed that allows reconstruction of the flow field obtained by an accurate model based on the flow field obtained by the simplified model. Spalart–Allmaras model with approximate nearwall domain decomposition and Spalart–Allmaras model resolving the near-wall region are taken as the simplified and the base models respectively. The operator is constructed using a local approach, i. e. to reconstruct a point in the flow field, only features (flow variables and their derivatives) at this point in the field are used. The operator is constructed using the Random Forest algorithm. The efficiency and accuracy of the obtained surrogate model are demonstrated on the supersonic flow over a compression corner with different values for angle $\alpha$ and Reynolds number. The investigation has been conducted into interpolation and extrapolation both by $Re$ and $\alpha$.

There are conditions of uneven combustion for tubular powder elements of large elongation used in artillery propelling charges. Here it is necessary to consider in parallel the processes of combustion and movement of powder gases inside and outside the channels of the powder tubes. Without this, it is impossible to adequately formulate and solve the problems of ignition, erosive combustion and stress-strain state of tubular powder elements in the shot process. The paper presents a physical and mathematical formulation of the main problem of the internal ballistics of an artillery shot for a charge consisting of a set of powder tubes. Combustion and movement of a bundle of powder tubes along the barrel channel is modeled by an equivalent tubular charge of all-round combustion. The end and cross-sectional areas of the channel of such a charge (equivalent tube) are equal to the sum of the areas of the ends and cross-sections of the channels of the powder tubes, respectively. The combustion surface of the channel is equal to the sum of the inner surfaces of the tubes in the bundle. The outer combustion surface of the equivalent tube is equal to the sum of the outer surfaces of the tubes in the bundle. It is assumed that the equivalent tube moves along the axis of the bore. The speed of motion of an equivalent tubular charge and its current position are determined from Newton’s second law. To calculate the flow parameters, we used two-dimensional axisymmetric equations of gas dynamics, for the solution of which an axisymmetric orthogonalized difference mesh is constructed, which adapts to the flow conditions. When the tube moves and burns, the difference grid is rearranged taking into account the changing regions of integration. The control volume method is used for the numerical solution of the system of gas-dynamic equations. The gas parameters at the boundaries of the control volumes are determined using a self-similar solution to the Godunov problem of decay for an arbitrary discontinuity. The developed technique was used to calculate the internal ballistics parameters of an artillery shot. This approach is considered for the first time and allows a new approach to the design of tubular artillery charges, since it allows obtaining the necessary information in the form of fields of velocity and pressure of powder gases for calculating the process of gradual ignition, unsteady erosive combustion, stress-strain state and strength of powder elements during the shot. The time dependences of the parameters of the internal ballistics process and the distribution of the main parameters of the flow of combustion products at different times are presented.

Migration has a significant impact on the shaping of the demographic structure of the territories population, the state of regional and local labour markets. As a rule, rapid change in the working-age population of any territory due to migration processes results in an imbalance in supply and demand on labour markets and a change in the demographic structure of the population. Migration is also to a large extent a reflection of socio-economic processes taking place in the society. Hence, the issues related to the study of migration factors, the direction, intensity and structure of migration flows, and the prediction of their magnitude are becoming topical issues these days.

Mathematical tools are often used to analyze, predict migration processes and assess their consequences, allowing for essentially accurate modelling of migration processes for different territories on the basis of the available statistical data. In recent years, quite a number of scientific papers on modelling internal and external migration flows using mathematical methods have appeared both in Russia and in foreign countries in recent years. Consequently, there has been a need to systematize the currently most commonly used methods and tools applied in migration modelling to form a coherent picture of the main trends and research directions in this field.

The presented review considers the main approaches to migration modelling and the main components of migration modelling methodology, i. e. stages, methods, models and model classification. Their comparative analysis was also conducted and general recommendations on the choice of mathematical tools for modelling were developed. The review contains two sections: migration modelling methods and migration models. The first section describes the main methods used in the model development process — econometric, cellular automata, system-dynamic, probabilistic, balance, optimization and cluster analysis. Based on the analysis of modern domestic and foreign publications on migration, the most common classes of models — regression, agent-based, simulation, optimization, probabilistic, balance, dynamic and combined — were identified and described. The features, advantages and disadvantages of different types of migration process models were considered.

The paper is devoted to the secondary use of spectrum in telecommunication networks. It is emphasized that one of the solutions to this problem is the use of cognitive radio technologies and dynamic spectrum access for the successful functioning of which a large amount of information is required, including the parameters of base stations and network subscribers. Storage and processing of information should be carried out using a radio environment map, which is a spatio-temporal database of all activity in the network and allows you to determine the frequencies available for use at a given time. The paper presents a two-level model for forming a map of the radio environment of a cellular communication system LTE, in which the local and global levels are highlighted, which is described by the following parameters: a set of frequencies, signal attenuation, signal propagation map, grid step, current time count. The key objects of the model are the base station and the subscriber unit. The main parameters of the base station include: name, identifier, cell coordinates, range number, radiation power, numbers of connected subscriber devices, dedicated resource blocks. For subscriber devices, the following parameters are used: name, identifier, location, current coordinates of the device cell, base station identifier, frequency range, numbers of resource blocks for communication with the station, radiation power, data transmission status, list of numbers of the nearest stations, schedules movement and communication sessions of devices. An algorithm for the implementation of the model is presented, taking into account the scenarios of movement and communication sessions of subscriber devices. A method for calculating a map of the radio environment at a point on a coordinate grid, taking into account losses during the propagation of radio signals from emitting devices, is presented. The software implementation of the model is performed using the MatLab package. The approaches are described that allow to increase the speed of its work. In the simulation, the choice of parameters was carried out taking into account the data of the existing communication systems and the economy of computing resources. The experimental results of the algorithm for the formation of a radio environment map are demonstrated, confirming the correctness of the developed model.

Since 1950s the field of city transport modelling has progressed rapidly. The first equilibrium distribution models of traffic flow appeared. The most popular model (which is still being widely used) was the Beckmann model, based on the two Wardrop principles. The core of the model could be briefly described as the search for the Nash equilibrium in a population demand game, in which losses of agents (drivers) are calculated based on the chosen path and demands of this path with correspondences being fixed. The demands (costs) of a path are calculated as the sum of the demands of different path segments (graph edges), that are included in the path. The costs of an edge (edge travel time) are determined by the amount of traffic on this edge (more traffic means larger travel time). The flow on a graph edge is determined by the sum of flows over all paths passing through the given edge. Thus, the cost of traveling along a path is determined not only by the choice of the path, but also by the paths other drivers have chosen. Thus, it is a standard game theory task. The way cost functions are constructed allows us to narrow the search for equilibrium to solving an optimization problem (game is potential in this case). If the cost functions are monotone and non-decreasing, the optimization problem is convex. Actually, different assumptions about the cost functions form different models. The most popular model is based on the BPR cost function. Such functions are massively used in calculations of real cities. However, in the beginning of the XXI century, Yu. E. Nesterov and A. de Palma showed that Beckmann-type models have serious weak points. Those could be fixed using the stable dynamics model, as it was called by the authors. The search for equilibrium here could be also reduced to an optimization problem, moreover, the problem of linear programming. In 2013, A.V.Gasnikov discovered that the stable dynamics model can be obtained by a passage to the limit in the Beckmann model. However, it was made only for several practically important, but still special cases. Generally, the question if this passage to the limit is possible remains open. In this paper, we provide the justification of the possibility of the above-mentioned passage to the limit in the general case, when the cost function for traveling along the edge as a function of the flow along the edge degenerates into a function equal to fixed costs until the capacity is reached and it is equal to plus infinity when the capacity is exceeded.

In Russian medicine two radiopharmaceuticals are currently used for radionuclide therapy of bone metastases: ⁸⁹Sr-chloride and ¹⁵³Sm-oxabifor. The first one has many side effects, so its use is limited. The second one is available only in clinics, its transportation to which does not take much time. Currently, the third radiopharmaceutical ¹⁸⁸Re-solerene is undergoing clinical trials. Due to the generator method of obtaining ¹⁸⁸Re, this radiopharmaceutical should become available for use in many regions of our country. Therefore, there is a need for a comparative analysis of the characteristics of these radiopharmaceuticals, including on the basis of mathematical modeling.

The article discusses the features of mathematical modeling the kinetics of osteotropic radiopharmaceutical drugs in the human body with bone metastases. Based on the four-compartment model, a complex of modeling and calculation of pharmacokinetic and dosimetric characteristics of radiopharmaceuticals for radionuclide therapy of bone metastases was developed and tested. Using clinical data, the transport constants of the model were identified and the individual characteristics of Russian radiopharmaceuticals labeled ⁸⁹Sr, 153Sm and ¹⁸⁸Re were calculated (effective half-lives, maximum activity in the compartments and the times of their achievement, absorbed doses to bone tissue and metastases, endosteal bone layer, red bone marrow, blood, kidneys and bladder). The time activity dependencies for all compartments of the model are obtained and analyzed. A comparative analysis of the pharmacokinetics and dosimetry of three radiopharmaceuticals (⁸⁹Sr-chloride, ¹⁵³Sm-oxabiphore, ¹⁸⁸Re-solerene) was carried out.

From a comparative analysis of the pharmacokinetic and dosimetric characteristics of these radiopharmaceutical drugs, it follows that the best of them for widespread use in many regions of our country should be ¹⁸⁸Re-solerene, taking into account the generator method of obtaining ¹⁸⁸Re in a hospital.

The paper presents an analysis of the nonlinear equation of spin wave transport by the method of characteristics. The conclusion of a new mathematical model of spin wave propagation is presented for the solution of which the characteristic is applied. The behavior analysis of the behavior of the real and imaginary parts of the wave and its amplitude is performed. The phase portraits demonstrate the dependence of the desired function on the nonlinearity coefficient. It is established that the real and imaginary parts of the wave oscillate by studying the nature of the evolution of the initial wave profile by the phase plane method. The transition of trajectories from an unstable focus to a limiting cycle, which corresponds to the oscillation of the real and imaginary parts, is shown. For the amplitude of the wave, such a transition is characterized by its amplification or attenuation (depending on the nonlinearity coefficient and the chosen initial conditions) up to a certain threshold value. It is shown that the time of the transition process from amplification (attenuation) to stabilization of the amplitude also depends on the nonlinearity parameter. It was found out that at the interval of amplification of the amplitude of the spin wave, the time of the transition process decreases, and lower amplitude values correspond to higher parameters of nonlinearity.

Rugose spiraling whitefly (RSW) is one of the major pests which affects the coconut trees. It feeds on the tree by sucking up the water content as well as the essential nutrients from leaves. It also forms sooty mold in leaves due to which the process of photosynthesis is inhibited. Biocontrol of pest is harmless for trees and crops. The experimental results in literature reveal that Pseudomallada astur is a potential predator for this pest. We investigate the dynamics of predator, Pseudomallada astur’s interaction with rugose spiralling whitefly, Aleurodicus rugioperculatus in coconut trees using a mathematical model. In this system of ordinary differential equation, the pest-predator interaction is modeled using Holling type III functional response. The parametric values are calculated from the experimental results and are tabulated. An approximate analytical solution for the system has been derived. The homotopy analysis method proves to be a suitable method for creating solutions that are valid even for moderate to large parameter values, hence we employ the same to solve this nonlinear model. The $\hbar$-curves, which give the admissible region of $\hbar$, are provided to validate the region of convergence. We have derived the approximate solution at fifth order and stopped at this order since we obtain a more approximate solution in this iteration. Numerical simulation is obtained through MATLAB. The analytical results are compared with numerical simulation and are found to be in good agreement. The biological interpretation of figures implies that the use of a predator reduces the whitefly’s growth to a greater extent.