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Modern methods of mathematical modeling of blood flow using reduced order methods
Computer Research and Modeling, 2018, v. 10, no. 5, pp. 581-604Views (last year): 62. Citations: 2 (RSCI).The study of the physiological and pathophysiological processes in the cardiovascular system is one of the important contemporary issues, which is addressed in many works. In this work, several approaches to the mathematical modelling of the blood flow are considered. They are based on the spatial order reduction and/or use a steady-state approach. Attention is paid to the discussion of the assumptions and suggestions, which are limiting the scope of such models. Some typical mathematical formulations are considered together with the brief review of their numerical implementation. In the first part, we discuss the models, which are based on the full spatial order reduction and/or use a steady-state approach. One of the most popular approaches exploits the analogy between the flow of the viscous fluid in the elastic tubes and the current in the electrical circuit. Such models can be used as an individual tool. They also used for the formulation of the boundary conditions in the models using one dimensional (1D) and three dimensional (3D) spatial coordinates. The use of the dynamical compartment models allows describing haemodynamics over an extended period (by order of tens of cardiac cycles and more). Then, the steady-state models are considered. They may use either total spatial reduction or two dimensional (2D) spatial coordinates. This approach is used for simulation the blood flow in the region of microcirculation. In the second part, we discuss the models, which are based on the spatial order reduction to the 1D coordinate. The models of this type require relatively small computational power relative to the 3D models. Within the scope of this approach, it is also possible to include all large vessels of the organism. The 1D models allow simulation of the haemodynamic parameters in every vessel, which is included in the model network. The structure and the parameters of such a network can be set according to the literature data. It also exists methods of medical data segmentation. The 1D models may be derived from the 3D Navier – Stokes equations either by asymptotic analysis or by integrating them over a volume. The major assumptions are symmetric flow and constant shape of the velocity profile over a cross-section. These assumptions are somewhat restrictive and arguable. Some of the current works paying attention to the 1D model’s validation, to the comparing different 1D models and the comparing 1D models with clinical data. The obtained results reveal acceptable accuracy. It allows concluding, that the 1D approach can be used in medical applications. 1D models allow describing several dynamical processes, such as pulse wave propagation, Korotkov’s tones. Some physiological conditions may be included in the 1D models: gravity force, muscles contraction force, regulation and autoregulation.
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Modeling the spatial scenario of the transition to chaos via torus breakup in the problem with concentration-dependent diffusion
Computer Research and Modeling, 2020, v. 12, no. 1, pp. 9-31In the last decades, universal scenarios of the transition to chaos in dynamic systems have been well studied. The scenario of the transition to chaos is defined as a sequence of bifurcations that occur in the system under the variation one of the governing parameters and lead to a qualitative change in dynamics, starting from the regular mode and ending with chaotic behavior. Typical scenarios include a cascade of period doubling bifurcations (Feigenbaum scenario), the breakup of a low-dimensional torus (Ruelle–Takens scenario), and the transition to chaos through the intermittency (Pomeau–Manneville scenario). In more complicated spatially distributed dynamic systems, the complexity of dynamic behavior growing with a parameter change is closely intertwined with the formation of spatial structures. However, the question of whether the spatial and temporal axes could completely exchange roles in some scenario still remains open. In this paper, for the first time, we propose a mathematical model of convection–diffusion–reaction, in which a spatial transition to chaos through the breakup of the quasi–periodic regime is realized in the framework of the Ruelle–Takens scenario. The physical system under consideration consists of two aqueous solutions of acid (A) and base (B), initially separated in space and placed in a vertically oriented Hele–Shaw cell subject to the gravity field. When the solutions are brought into contact, the frontal neutralization reaction of the second order A + B $\to$ C begins, which is accompanied by the production of salt (C). The process is characterized by a strong dependence of the diffusion coefficients of the reagents on their concentration, which leads to the appearance of two local zones of reduced density, in which chemoconvective fluid motions develop independently. Although the layers, in which convection develops, all the time remain separated by the interlayer of motionless fluid, they can influence each other via a diffusion of reagents through this interlayer. The emerging chemoconvective structure is the modulated standing wave that gradually breaks down over time, repeating the sequence of the bifurcation chain of the Ruelle–Takens scenario. We show that during the evolution of the system one of the spatial axes, directed along the reaction front, plays the role of time, and time itself starts to play the role of a control parameter.
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Stationary states and bifurcations in a one-dimensional active medium of oscillators
Computer Research and Modeling, 2023, v. 15, no. 3, pp. 491-512This article presents the results of an analytical and computer study of the collective dynamic properties of a chain of self-oscillating systems (conditionally — oscillators). It is assumed that the couplings of individual elements of the chain are non-reciprocal, unidirectional. More precisely, it is assumed that each element of the chain is under the influence of the previous one, while the reverse reaction is absent (physically insignificant). This is the main feature of the chain. This system can be interpreted as an active discrete medium with unidirectional transfer, in particular, the transfer of a matter. Such chains can represent mathematical models of real systems having a lattice structure that occur in various fields of natural science and technology: physics, chemistry, biology, radio engineering, economics, etc. They can also represent models of technological and computational processes. Nonlinear self-oscillating systems (conditionally, oscillators) with a wide “spectrum” of potentially possible individual self-oscillations, from periodic to chaotic, were chosen as the “elements” of the lattice. This allows one to explore various dynamic modes of the chain from regular to chaotic, changing the parameters of the elements and not changing the nature of the elements themselves. The joint application of qualitative methods of the theory of dynamical systems and qualitative-numerical methods allows one to obtain a clear picture of all possible dynamic regimes of the chain. The conditions for the existence and stability of spatially-homogeneous dynamic regimes (deterministic and chaotic) of the chain are studied. The analytical results are illustrated by a numerical experiment. The dynamical regimes of the chain are studied under perturbations of parameters at its boundary. The possibility of controlling the dynamic regimes of the chain by turning on the necessary perturbation at the boundary is shown. Various cases of the dynamics of chains comprised of inhomogeneous (different in their parameters) elements are considered. The global chaotic synchronization (of all oscillators in the chain) is studied analytically and numerically.
Keywords: dynamical system, lattice, bifurcations, oscillator, phase space, dynamical chaos, synchronization. -
The mechanism of formation of oscillons — localized oscillatory structures
Computer Research and Modeling, 2015, v. 7, no. 6, pp. 1177-1184Views (last year): 6. Citations: 1 (RSCI).A formal model mechanism of oscillon formation is proposed. These structures were found in a variety of physical systems and a chemical Belousov–Jabotinsky reaction proceeding in an aerosol OT water-inoil microemulsion. Via the proposed mechanism oscillons occur as a result of interaction of two subsystems. In the first subsystem for a proper set of parameters solitary stationary structures may arise as a result of hard local excitation. These structures influence spatial distribution of the second subsystem parameter that leads to local oscillations in the subsystem.
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Simulation of unsteady structure of flow over descent module in the Martian atmosphere conditions
Computer Research and Modeling, 2022, v. 14, no. 4, pp. 701-714The article presents the results of numerical modeling of the vortex spatial non-stationary motion of the medium arising near the lateral and bottom surfaces of the descent module during its movement in the atmosphere of Mars. The numerical study was performed for the high-speed streamline regime at various angles of attack. Mathematical modeling was carried out on the basis of the Navier – Stokes model and the model of equilibrium chemical reactions for the Martian atmosphere gas. The simulation results showed that under the considered conditions of the descent module motion, a non-stationary flow with a pronounced vortex character is realized near its lateral and bottom surfaces. Numerical calculations indicate that, depending on the angle of attack, the nonstationarity and vortex nature of the flow can manifest itself both on the entire lateral and bottom surfaces of the module, and, partially, on their leeward side. For various angles of attack, pictures of the vortex structure of the flow near the surface of the descent vehicle and in its near wake are presented, as well as pictures of the gas-dynamic parameters fields. The non-stationary nature of the flow is confirmed by the presented time dependences of the gas-dynamic parameters of the flow at various points on the module surface. The carried out parametric calculations made it possible to determine the dependence of the aerodynamic characteristics of the descent module on the angle of attack. Mathematical modeling is carried out on the basis of the conservative numerical method of fluxes, which is a finitevolume method based on a finite-difference writing of the conservation laws of additive characteristics of the medium using «upwind» approximations of stream variables. To simulate the complex vortex structure of the flow over descent module, the nonuniform computational grids are used, including up to 30 million finite volumes with exponential thickening to the surface, which made it possible to reveal small-scale vortex formations. Numerical investigations were carried out on the basis of the developed software package based on parallel algorithms of the used numerical method and implemented on modern multiprocessor computer systems. The results of numerical simulation presented in the article were obtained using up to two thousand computing cores of a multiprocessor complex.
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Excitement of solitons in the interaction of kinks of sine-Gordon equation with attracting impurity
Computer Research and Modeling, 2012, v. 4, no. 3, pp. 509-520Citations: 5 (RSCI).We investigate analytically and numerically the structure and properties of localized two- and three-kink solutions of the sine-Gordon equation, which are excited in the region of the attracting impurity. We have considered cases of single and double spatially extended impurity.
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Traveling waves in a parabolic problem with a rotation on the circle
Computer Research and Modeling, 2017, v. 9, no. 5, pp. 705-716Views (last year): 11. Citations: 5 (RSCI).Optical systems with two-dimensional feedback demonstrate wide possibilities for studying the nucleation and development processes of dissipative structures. Feedback allows to influence the dynamics of the optical system by controlling the transformation of spatial variables performed by prisms, lenses, dynamic holograms and other devices. A nonlinear interferometer with a mirror image of a field in two-dimensional feedback is one of the simplest optical systems in which is realized the nonlocal nature of light fields.
A mathematical model of optical systems with two-dimensional feedback is a nonlinear parabolic equation with rotation transformation of a spatial variable and periodicity conditions on a circle. Such problems are investigated: bifurcation of the traveling wave type stationary structures, how the form of the solution changes as the diffusion coefficient decreases, dynamics of the solution’s stability when the bifurcation parameter leaves the critical value. For the first time as a parameter bifurcation was taken of diffusion coefficient.
The method of central manifolds and the Galerkin’s method are used in this paper. The method of central manifolds and the Galerkin’s method are used in this paper. The method of central manifolds allows to prove a theorem on the existence and form of the traveling wave type solution neighborhood of the bifurcation value. The first traveling wave born as a result of the Andronov –Hopf bifurcation in the transition of the bifurcation parameter through the сritical value. According to the central manifold theorem, the first traveling wave is born orbitally stable.
Since the above theorem gives the opportunity to explore solutions are born only in the vicinity of the critical values of the bifurcation parameter, the decision to study the dynamics of traveling waves of change during the withdrawal of the bifurcation parameter in the supercritical region, the formalism of the Galerkin method was used. In accordance with the method of the central manifold is made Galerkin’s approximation of the problem solution. As the bifurcation parameter decreases and its transition through the critical value, the zero solution of the problem loses stability in an oscillatory manner. As a result, a periodic solution of the traveling wave type branches off from the zero solution. This wave is born orbitally stable. With further reduction of the parameter and its passage through the next critical value from the zero solution, the second solution of the traveling wave type is produced as a result of the Andronov –Hopf bifurcation. This wave is born unstable with an instability index of two.
Numerical calculations have shown that the application of the Galerkin’s method leads to correct results. The results obtained are in good agreement with the results obtained by other authors and can be used to establish experiments on the study of phenomena in optical systems with feedback.
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Investigation of Turing structures formation under the influence of wave instability
Computer Research and Modeling, 2019, v. 11, no. 3, pp. 397-412Views (last year): 21.A classical for nonlinear dynamics model, Brusselator, is considered, being augmented by addition of a third variable, which plays the role of a fast-diffusing inhibitor. The model is investigated in one-dimensional case in the parametric domain, where two types of diffusive instabilities of system’s homogeneous stationary state are manifested: wave instability, which leads to spontaneous formation of autowaves, and Turing instability, which leads to spontaneous formation of stationary dissipative structures, or Turing structures. It is shown that, due to the subcritical nature of Turing bifurcation, the interaction of two instabilities in this system results in spontaneous formation of stationary dissipative structures already before the passage of Turing bifurcation. In response to different perturbations of spatially uniform stationary state, different stable regimes are manifested in the vicinity of the double bifurcation point in the parametric region under study: both pure regimes, which consist of either stationary or autowave dissipative structures; and mixed regimes, in which different modes dominate in different areas of the computational space. In the considered region of the parametric space, the system is multistable and exhibits high sensitivity to initial noise conditions, which leads to blurring of the boundaries between qualitatively different regimes in the parametric region. At that, even in the area of dominance of mixed modes with prevalence of Turing structures, the establishment of a pure autowave regime has significant probability. In the case of stable mixed regimes, a sufficiently strong local perturbation in the area of the computational space, where autowave mode is manifested, can initiate local formation of new stationary dissipative structures. Local perturbation of the stationary homogeneous state in the parametric region under investidation leads to a qualitatively similar map of established modes, the zone of dominance of pure autowave regimes being expanded with the increase of local perturbation amplitude. In two-dimensional case, mixed regimes turn out to be only transient — upon the appearance of localized Turing structures under the influence of wave regime, they eventually occupy all available space.
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Localized nonlinear waves of the sine-Gordon equation in a model with three extended impurities
Computer Research and Modeling, 2024, v. 16, no. 4, pp. 855-868In this work, we use analytical and numerical methods to consider the problem of the structure and dynamics of coupled localized nonlinear waves in the sine-Gordon model with three identical attractive extended “impurities”, which are modeled by spatial inhomogeneity of the periodic potential. Two possible types of coupled nonlinear localized waves are found: breather and soliton. The influence of system parameters and initial conditions on the structure, amplitude, and frequency of localized waves was analyzed. Associated oscillations of localized waves of the breather type as in the case of point impurities, are the sum of three harmonic oscillations: in-phase, in-phase-antiphase and antiphase type. Frequency analysis of impurity-localized waves that were obtained during a numerical experiment was performed using discrete Fourier transform. To analyze localized breather-type waves, the numerical finite difference method was used. To carry out a qualitative analysis of the obtained numerical results, the problem was solved analytically for the case of small amplitudes of oscillations localized on impurities. It is shown that, for certain impurity parameters (depth and width), it is possible to obtain localized solitontype waves. The ranges of values of the system parameters in which localized waves of a certain type exist, as well as the region of transition from breather to soliton types of oscillations, have been found. The values of the depth and width of the impurity at which a transition from the breather to the soliton type of localized oscillations is observed were determined. Various scenarios of soliton-type oscillations with negative and positive amplitude values for all three impurities, as well as mixed cases, were obtained and considered. It is shown that in the case when the distance between impurities much less than one, there is no transition region where which the nascent breather, after losing energy through radiation, transforms into a soliton. It is shown that the considered model can be used, for example, to describe the dynamics of magnetization waves in multilayer magnets.
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Marks of stochastic determinacy of forest ecosystem autogenous succession in Markov models
Computer Research and Modeling, 2016, v. 8, no. 2, pp. 255-265Views (last year): 2. Citations: 2 (RSCI).This article describes a method to model the course of forest ecosystem succession to the climax state by means of a Markov chain. In contrast to traditional methods of forest succession modelling based on changes of vegetation types, several variants of the vertical structure of communities formed by late-successional tree species are taken as the transition states of the model. Durations of succession courses from any stage are not set in absolute time units, but calculated as the average number of steps before reaching the climax in a unified time scale. The regularities of succession courses are revealed in the proper time of forest ecosystems shaping. The evidences are obtained that internal features of the spatial and population structure do stochastically determine the course and the pace of forest succession. The property of developing vegetation of forest communities is defined as an attribute of stochastic determinism in the course of autogenous succession.
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