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Random forest of risk factors as a predictive tool for adverse events in clinical medicine
Computer Research and Modeling, 2025, v. 17, no. 5, pp. 987-1004The aim of study was to develop an ensemble machine learning method for constructing interpretable predictive models and to validate it using the example of predicting in-hospital mortality (IHM) in patients with ST-segment elevation myocardial infarction (STEMI).
A retrospective cohort study was conducted using data from 5446 electronic medical records of STEMI patients who underwent percutaneous coronary intervention (PCI). Patients were divided into two groups: 335 (6.2%) patients who died during hospitalization and 5111 (93.8%) patients with a favourable in-hospital outcome. A pool of potential predictors was formed using statistical methods. Through multimetric categorization (minimizing p-values, maximizing the area under the ROC curve (AUC), and SHAP value analysis), decision trees, and multivariable logistic regression (MLR), predictors were transformed into risk factors for IHM. Predictive models for IHM were developed using MLR, Random Forest Risk Factors (RandFRF), Stochastic Gradient Boosting (XGboost), Random Forest (RF), Adaptive boosting, Gradient Boosting, Light Gradient-Boosting Machine, Categorical Boosting (CatBoost), Explainable Boosting Machine and Stacking methods.
Authors developed the RandFRF method, which integrates the predictive outcomes of modified decision trees, identifies risk factors and ranks them based on their contribution to the risk of adverse outcomes. RandFRF enables the development of predictive models with high discriminative performance (AUC 0.908), comparable to models based on CatBoost and Stacking (AUC 0.904 and 0.908, respectively). In turn, risk factors provide clinicians with information on the patient’s risk group classification and the extent of their impact on the probability of IHM. The risk factors identified by RandFRF can serve not only as rationale for the prediction results but also as a basis for developing more accurate models.
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A novel method of stylometry based on the statistic of numerals
Computer Research and Modeling, 2017, v. 9, no. 5, pp. 837-850A new method of statistical analysis of texts is suggested. The frequency distribution of the first significant digits in numerals of English-language texts is considered. We have taken into account cardinal as well as ordinal numerals expressed both in figures, and verbally. To identify the author’s use of numerals, we previously deleted from the text all idiomatic expressions and set phrases accidentally containing numerals, as well as itemizations and page numbers, etc. Benford’s law is found to hold approximately for the frequencies of various first significant digits of compound literary texts by different authors; a marked predominance of the digit 1 is observed. In coherent authorial texts, characteristic deviations from Benford’s law arise which are statistically stable significant author peculiarities that allow, under certain conditions, to consider the problem of authorship and distinguish between texts by different authors. The text should be large enough (at least about 200 kB). At the end of $\{1, 2, \ldots, 9\}$ digits row, the frequency distribution is subject to strong fluctuations and thus unrepresentative for our purpose. The aim of the theoretical explanation of the observed empirical regularity is not intended, which, however, does not preclude the applicability of the proposed methodology for text attribution. The approach suggested and the conclusions are backed by the examples of the computer analysis of works by W.M. Thackeray, M. Twain, R. L. Stevenson, J. Joyce, sisters Bront¨e, and J.Austen. On the basis of technique suggested, we examined the authorship of a text earlier ascribed to L. F. Baum (the result agrees with that obtained by different means). We have shown that the authorship of Harper Lee’s “To Kill a Mockingbird” pertains to her, whereas the primary draft, “Go Set a Watchman”, seems to have been written in collaboration with Truman Capote. All results are confirmed on the basis of parametric Pearson’s chi-squared test as well as non-parametric Mann –Whitney U test and Kruskal –Wallis test.
Keywords: text attribution, first significant digit of numerals.Views (last year): 10. -
Modelling interregional migration flows by the cellular automata
Computer Research and Modeling, 2020, v. 12, no. 6, pp. 1467-1483The article dwells upon investigating the issue of the most adequate tools developing and justifying to forecast the interregional migration flows value and structure. Migration processes have a significant impact on the size and demographic structure of the population of territories, the state and balance of regional and local labor markets.
To analyze the migration processes and to assess their impact an economic-mathematical tool is required which would be instrumental in modelling the migration processes and flows for different areas with the desired precision. The current methods and approaches to the migration processes modelling, including the analysis of their advantages and disadvantages, were considered. It is noted that to implement many of these methods mass aggregated statistical data is required which is not always available and doesn’t characterize the migrants behavior at the local level where the decision to move to a new dwelling place is made. This has a significant impact on the ability to apply appropriate migration processes modelling techniques and on the projection accuracy of the migration flows magnitude and structure.
The cellular automata model for interregional migration flows modelling, implementing the integration of the households migration behavior model under the conditions of the Bounded Rationality into the general model of the area migration flow was developed and tested based on the Primorye Territory data. To implement the households migration behavior model under the conditions of the Bounded Rationality the integral attractiveness index of the regions with economic, social and ecological components was proposed in the work.
To evaluate the prognostic capacity of the developed model, it was compared with the available cellular automata models used to predict interregional migration flows. The out of sample prediction method which showed statistically significant superiority of the proposed model was applied for this purpose. The model allows obtaining the forecasts and quantitative characteristics of the areas migration flows based on the households real migration behaviour at the local level taking into consideration their living conditions and behavioural motives.
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Bibliographic link prediction using contrast resampling technique
Computer Research and Modeling, 2021, v. 13, no. 6, pp. 1317-1336The paper studies the problem of searching for fragments with missing bibliographic links in a scientific article using automatic binary classification. To train the model, we propose a new contrast resampling technique, the innovation of which is the consideration of the context of the link, taking into account the boundaries of the fragment, which mostly affects the probability of presence of a bibliographic links in it. The training set was formed of automatically labeled samples that are fragments of three sentences with class labels «without link» and «with link» that satisfy the requirement of contrast: samples of different classes are distanced in the source text. The feature space was built automatically based on the term occurrence statistics and was expanded by constructing additional features — entities (names, numbers, quotes and abbreviations) recognized in the text.
A series of experiments was carried out on the archives of the scientific journals «Law enforcement review» (273 articles) and «Journal Infectology» (684 articles). The classification was carried out by the models Nearest Neighbors, RBF SVM, Random Forest, Multilayer Perceptron, with the selection of optimal hyperparameters for each classifier.
Experiments have confirmed the hypothesis put forward. The highest accuracy was reached by the neural network classifier (95%), which is however not as fast as the linear one that showed also high accuracy with contrast resampling (91–94%). These values are superior to those reported for NER and Sentiment Analysis on comparable data. The high computational efficiency of the proposed method makes it possible to integrate it into applied systems and to process documents online.
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Changepoint detection in biometric data: retrospective nonparametric segmentation methods based on dynamic programming and sliding windows
Computer Research and Modeling, 2024, v. 16, no. 5, pp. 1295-1321This paper is dedicated to the analysis of medical and biological data obtained through locomotor training and testing of astronauts conducted both on Earth and during spaceflight. These experiments can be described as the astronaut’s movement on a treadmill according to a predefined regimen in various speed modes. During these modes, not only the speed is recorded but also a range of parameters, including heart rate, ground reaction force, and others, are collected. In order to analyze the dynamics of the astronaut’s condition over an extended period, it is necessary to perform a qualitative segmentation of their movement modes to independently assess the target metrics. This task becomes particularly relevant in the development of an autonomous life support system for astronauts that operates without direct supervision from Earth. The segmentation of target data is complicated by the presence of various anomalies, such as deviations from the predefined regimen, arbitrary and varying duration of mode transitions, hardware failures, and other factors. The paper includes a detailed review of several contemporary retrospective (offline) nonparametric methods for detecting multiple changepoints, which refer to sudden changes in the properties of the observed time series occurring at unknown moments. Special attention is given to algorithms and statistical measures that determine the homogeneity of the data and methods for detecting change points. The paper considers approaches based on dynamic programming and sliding window methods. The second part of the paper focuses on the numerical modeling of these methods using characteristic examples of experimental data, including both “simple” and “complex” speed profiles of movement. The analysis conducted allowed us to identify the preferred methods, which will be further evaluated on the complete dataset. Preference is given to methods that ensure the closeness of the markup to a reference one, potentially allow the detection of both boundaries of transient processes, as well as are robust relative to internal parameters.
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Statistically fair price for the European call options according to the discreet mean/variance model
Computer Research and Modeling, 2014, v. 6, no. 5, pp. 861-874Views (last year): 1.We consider a portfolio with call option and the corresponding underlying asset under the standard assumption that stock-market price represents a random variable with lognormal distribution. Minimizing the variance hedging risk of the portfolio on the date of maturity of the call option we find a fraction of the asset per unit call option. As a direct consequence we derive the statistically fair lookback call option price in explicit form. In contrast to the famous Black–Scholes theory, any portfolio cannot be regarded as risk-free because no additional transactions are supposed to be conducted over the life of the contract, but the sequence of independent portfolios will reduce risk to zero asymptotically. This property is illustrated in the experimental section using a dataset of daily stock prices of 37 leading US-based companies for the period from April 2006 to January 2013.
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Statistical analysis of bigrams of specialized texts
Computer Research and Modeling, 2020, v. 12, no. 1, pp. 243-254The method of the stochastic matrix spectrum analysis is used to build an indicator that allows to determine the subject of scientific texts without keywords usage. This matrix is a matrix of conditional probabilities of bigrams, built on the statistics of the alphabet characters in the text without spaces, numbers and punctuation marks. Scientific texts are classified according to the mutual arrangement of invariant subspaces of the matrix of conditional probabilities of pairs of letter combinations. The separation indicator is the value of the cosine of the angle between the right and left eigenvectors corresponding to the maximum and minimum eigenvalues. The computational algorithm uses a special representation of the dichotomy parameter, which is the integral of the square norm of the resolvent of the stochastic matrix of bigrams along the circumference of a given radius in the complex plane. The tendency of the integral to infinity testifies to the approximation of the integration circuit to the eigenvalue of the matrix. The paper presents the typical distribution of the indicator of identification of specialties. For statistical analysis were analyzed dissertations on the main 19 specialties without taking into account the classification within the specialty, 20 texts for the specialty. It was found that the empirical distributions of the cosine of the angle for the mathematical and Humanities specialties do not have a common domain, so they can be formally divided by the value of this indicator without errors. Although the body of texts was not particularly large, nevertheless, in the case of arbitrary selection of dissertations, the identification error at the level of 2 % seems to be a very good result compared to the methods based on semantic analysis. It was also found that it is possible to make a text pattern for each of the specialties in the form of a reference matrix of bigrams, in the vicinity of which in the norm of summable functions it is possible to accurately identify the theme of the written scientific work, without using keywords. The proposed method can be used as a comparative indicator of greater or lesser severity of the scientific text or as an indicator of compliance of the text to a certain scientific level.
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Mathematical models of combat and military operations
Computer Research and Modeling, 2020, v. 12, no. 4, pp. 907-920Modeling the fight against terrorist, pirate and robbery acts at sea is an urgent scientific task due to the prevalence of force acts and the insufficient number of works on this issue. The actions of pirates and terrorists are diverse. Using a base ship, they can attack ships up to 450–500 miles from the coast. Having chosen the target, they pursue it and use the weapons to board the ship. Actions to free a ship captured by pirates or terrorists include: blocking the ship, predicting where pirates might be on the ship, penetrating (from board to board, by air or from under water) and cleaning up the ship’s premises. An analysis of the special literature on the actions of pirates and terrorists showed that the act of force (and actions to neutralize it) consists of two stages: firstly, blocking the vessel, which consists in forcing it to stop, and secondly, neutralizing the team (terrorist groups, pirates), including penetration of a ship (ship) and its cleaning. The stages of the cycle are matched by indicators — the probability of blocking and the probability of neutralization. The variables of the act of force model are the number of ships (ships, boats) of the attackers and defenders, as well as the strength of the capture group of the attackers and the crew of the ship - the victim of the attack. Model parameters (indicators of naval and combat superiority) were estimated using the maximum likelihood method using an international database of incidents at sea. The values of these parameters are 7.6–8.5. Such high values of superiority parameters reflect the parties' ability to act in force acts. An analytical method for calculating excellence parameters is proposed and statistically substantiated. The following indicators are taken into account in the model: the ability of the parties to detect the enemy, the speed and maneuverability characteristics of the vessels, the height of the vessel and the characteristics of the boarding equipment, the characteristics of weapons and protective equipment, etc. Using the Becker model and the theory of discrete choice, the probability of failure of the force act is estimated. The significance of the obtained models for combating acts of force in the sea space lies in the possibility of quantitative substantiation of measures to protect the ship from pirate and terrorist attacks and deterrence measures aimed at preventing attacks (the presence of armed guards on board the ship, assistance from warships and helicopters).
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Modernization as a global process: the experience of mathematical modeling
Computer Research and Modeling, 2021, v. 13, no. 4, pp. 859-873The article analyzes empirical data on the long-term demographic and economic dynamics of the countries of the world for the period from the beginning of the 19th century to the present. Population and GDP of a number of countries of the world for the period 1500–2016 were selected as indicators characterizing the long-term demographic and economic dynamics of the countries of the world. Countries were chosen in such a way that they included representatives with different levels of development (developed and developing countries), as well as countries from different regions of the world (North America, South America, Europe, Asia, Africa). A specially developed mathematical model was used for modeling and data processing. The presented model is an autonomous system of differential equations that describes the processes of socio-economic modernization, including the process of transition from an agrarian society to an industrial and post-industrial one. The model contains the idea that the process of modernization begins with the emergence of an innovative sector in a traditional society, developing on the basis of new technologies. The population is gradually moving from the traditional sector to the innovation sector. Modernization is completed when most of the population moves to the innovation sector.
Statistical methods of data processing and Big Data methods, including hierarchical clustering were used. Using the developed algorithm based on the random descent method, the parameters of the model were identified and verified on the basis of empirical series, and the model was tested using statistical data reflecting the changes observed in developed and developing countries during the period of modernization taking place over the past centuries. Testing the model has demonstrated its high quality — the deviations of the calculated curves from statistical data are usually small and occur during periods of wars and economic crises. Thus, the analysis of statistical data on the long-term demographic and economic dynamics of the countries of the world made it possible to determine general patterns and formalize them in the form of a mathematical model. The model will be used to forecast demographic and economic dynamics in different countries of the world.
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Comparative analysis of statistical methods of scientific publications classification in medicine
Computer Research and Modeling, 2020, v. 12, no. 4, pp. 921-933In this paper the various methods of machine classification of scientific texts by thematic sections on the example of publications in specialized medical journals published by Springer are compared. The corpus of texts was studied in five sections: pharmacology/toxicology, cardiology, immunology, neurology and oncology. We considered both classification methods based on the analysis of annotations and keywords, and classification methods based on the processing of actual texts. Methods of Bayesian classification, reference vectors, and reference letter combinations were applied. It is shown that the method of classification with the best accuracy is based on creating a library of standards of letter trigrams that correspond to texts of a certain subject. It is turned out that for this corpus the Bayesian method gives an error of about 20%, the support vector machine has error of order 10%, and the proximity of the distribution of three-letter text to the standard theme gives an error of about 5%, which allows to rank these methods to the use of artificial intelligence in the task of text classification by industry specialties. It is important that the support vector method provides the same accuracy when analyzing annotations as when analyzing full texts, which is important for reducing the number of operations for large text corpus.
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