Most cited papers (RSCI)

41. Tokarev A.A., Butylin A.A., Ataullakhanov F.I.
    Platelet transport and adhesion in shear blood flow: the role of erythrocytes
    Computer Research and Modeling, 2012, v. 4, no. 1, pp. 185-200

    Hemostatic system serves the organism for urgent repairs of damaged blood vessel walls. Its main components – platelets, the smallest blood cells, – are constantly contained in blood and quickly adhere to the site of injury. Platelet migration across blood flow and their hit with the wall are governed by blood flow conditions and, in particular, by the physical presence of other blood cells – erythrocytes. In this review we consider the main regularities of this influence, available mathematical models of platelet migration across blood flow and adhesion based on "convection-diffusion" PDEs, and discuss recent advances in this field. Understanding of the mechanisms of these processes is necessary for building of adequate mathematical models of hemostatic system functioning in blood flow in normal and pathological conditions.

    Keywords: platelets, blood flow, shear flow, segregation of suspensions, cell adhesion, convection-diffusion partial differential equations.
    Views (last year): 3. Citations: 8 (RSCI).
42. Khruschev S.S., Abaturova A.M., Diakonova A.N., Ustinin D.M., Zlenko D.V., Fedorov V.A., Kovalenko I.B., Riznichenko G.Yu., Rubin A.B.
    Multi-particle Brownian Dynamics software ProKSim for protein-protein interactions modeling
    Computer Research and Modeling, 2013, v. 5, no. 1, pp. 47-64

    Protein-protein interactions are of central importance for virtually every process in living matter. Modeling the dynamics of protein association is crucial for understanding their functionality. This paper proposes novel simulation software ProKSim (Protein Kinetics Simulator) for modeling of protein interactions by means of the multi-particle Brownian Dynamics. Effect of long-range electrostatic interactions on the process of transient encounter complex formation is numerically estimated. Investigation of transient encounter complex formation was performed for three pairs of proteins: ferredoxin and ferredoxin:NADP⁺-redustase, plastocyanin and cytochrome f, barnase and barstar.

    Keywords: multi-particle Brownian Dynamics, protein-protein recognition, molecular recognition.
    Views (last year): 4. Citations: 8 (RSCI).
43. Krivovichev G.V.
    On the computation of viscous fluid flows by the lattice Boltzmann method
    Computer Research and Modeling, 2013, v. 5, no. 2, pp. 165-178

    Modification of the lattice Boltzmann method for computation of viscous Newtonian fluid flows is considered. Modified method is based on the splitting of differential operator in Navier–Stokes equation and on the idea of instantaneous Maxwellisation of distribution function. The problems for the system of lattice kinetic equations and for the system of linear diffusion equations are solved while one time step is realized. The efficiency of the method proposed in comparison with the ordinary lattice Boltzmann method is demonstrated on the solution of the problem of planar flow in cavern in wide range of Reynolds number and various grid resolution.

    Keywords: lattice Boltzmann method, splitting method, cavern flow problem.
    Citations: 8 (RSCI).
44. Zakharov A.P., Bratsun D.A.
    Synchronization of circadian rhythms in the scale of a gene, a cell and a whole organism
    Computer Research and Modeling, 2013, v. 5, no. 2, pp. 255-270

    In the paper three characteristic scales of a biological system are proposed: microscopic (gene's size), mesoscopic (cell’s size) and macroscopic level (organism’s size). For each case the approach to modeling of circadian rhythms is discussed on the base of a time-delay model. At gene’s scale the stochastic description has been used. The robustness of rhythms mechanism to the fluctuations has been demonstrated. At the mesoscopic scale we propose the deterministic description within the spatially extended model. It was found the effect of collective synchronization of rhythms in cells. Macroscopic effects have been studied within the discrete model describing the collective behaviour of large amount of cells. The problem of cross-linking of results obtained at different scales is discussed. The comparison with experimental data is given.

    Keywords: circadian rhythms, synchronization, time-delay system.
    Views (last year): 1. Citations: 8 (RSCI).
45. Andruschenko V.A., Shevelev Yu.D.
    The Earth attack from space — the chronicle of centure
    Computer Research and Modeling, 2013, v. 5, no. 6, pp. 907-916

    Relevance of the problem of asteroid and comet impact hazard is considered. The short list of falling of space bodies to the Earth and their flights about it on distances, smaller  distances to the Moon, for the last 100 years is carried out. The question about  development of the federal research program on space protection of our planet and its integration into the international program is raised.

    Keywords: asteroid and comet impact hazards, potentially dangerous objects, Torino and Polermo scales, register of methods of prevention cosmic hazard.
    Views (last year): 2. Citations: 8 (RSCI).
46. Zhluktov S.V., Aksenov A.A., Karasev P.I.
    Modeling bypass transition within $k-\varepsilon$ approach
    Computer Research and Modeling, 2014, v. 6, no. 6, pp. 879-888

    This article is dedicated to investigation of the possibility to predict bypass transition by means of an unsophisticated low-Reynolds $k-\varepsilon$ turbulence model. Such a model has been developed at TESIS Ltd. The model is implemented in the FlowVision software suit. The ideas implemented in the model are discussed in the article. The capability of the model to predict bypass transition is demonstrated on well-known test cases T3B, T3A, T3A-.

    Keywords: turbulent flow, bypass transition, low-Reynolds $k-\varepsilon$ turbulence model, grid convergence.
    Views (last year): 11. Citations: 8 (RSCI).
47. Shumixin A.G., Boyarshinova A.S.
    Algorithm of artificial neural network architecture and training set size configuration within approximation of dynamic object behavior
    Computer Research and Modeling, 2015, v. 7, no. 2, pp. 243-251

    The article presents an approach to configuration of an artificial neural network architecture and a training set size. Configuration is based on parameter minimization with constraints specifying neural network model quality criteria. The algorithm of artificial neural network architecture and training set size configuration is applied to dynamic object artificial neural network approximation.
    Series of computational experiments were performed. The method is applicable to construction of dynamic object models based on non-linear autocorrelation neural networks.

    Keywords: dynamic object model, training set, artificial neural network, architecture, training, optimization of artificial neural network architecture.
    Views (last year): 2. Citations: 8 (RSCI).
48. Bogdanov A.V., Degtyarev A.B., Khramushin V.N.
    High performance computations on hybrid systems: will "grand challenges" be solved?
    Computer Research and Modeling, 2015, v. 7, no. 3, pp. 429-437

    Based on CFD computations we provide the analysis of the possibilities for using modern hybrid distributed computational environments for large complex system simulation. We argue that only multilevel approach supported by new mathematical models of transport properties, dynamical representation of the problem with transport and internal processes separated, and modern paradigm of programming, taking into account specific properties of heterogeneous system, will make it possible to scale the problem effectively.

    Keywords: hybrid system, “grand challenges”, tensor mathematics, aerohydrodynamics, computational experiment.
    Views (last year): 7. Citations: 8 (RSCI).
49. Aronov I.Z., Maksimova O.V., Zazhigalkin A.V.
    Investigation of time to reach consensus on the work of technical committees on standardization based on regular Markov chains
    Computer Research and Modeling, 2015, v. 7, no. 4, pp. 941-950

    In this paper construct the mathematical model for consensus in technical committees for standardization (TC), based on the consensus model proposed DeGroot. The basic problems of achieving consensus in the development of consensus standards in terms of the proposed model are discussed. The results of statistical modeling characterizing the dependence of time to reach consensus on the number of members of the TC and their authoritarianism are presented. It has been shown that increasing the number of TC experts and authoritarianism negative impact on the time to reach a consensus and increase fragmentation of the TC.

    Keywords: technical standardization committees, consensus, standards, regular Markov chains, time to reach consensus.
    Views (last year): 5. Citations: 8 (RSCI).
50. Aksenov A.A.
    FlowVision: Industrial computational fluid dynamics
    Computer Research and Modeling, 2017, v. 9, no. 1, pp. 5-20

    The work submits new release of the FlowVision software designed for automation of engineering calculations in computational fluid dynamics: FlowVision 3.09.05. The FlowVision software is used for solving different industrial problems. Its popularity is based on the capability to solve complex non-tradition problems involving different physical processes. The paradigm of complete automation of labor-intensive and time-taking processes like grid generation makes FlowVision attractive for many engineers. FlowVision is completely developer-independent software. It includes an advanced graphical interface, the system for specifying a computational project as well as the system for flow visualization on planes, on curvilinear surfaces and in volume by means of different methods: plots, color contours, iso-lines, iso-surfaces, vector fields. Besides that, FlowVision provides tools for calculation of integral characteristics on surfaces and in volumetric regions.

    The software is based on the finite-volume approach to approximation of the partial differential equations describing fluid motion and accompanying physical processes. It provides explicit and implicit methods for time integration of these equations. The software includes automated generator of unstructured grid with capability of its local dynamic adaptation. The solver involves two-level parallelism which allows calculations on computers with distributed and shared memory (coexisting in the same hardware). FlowVision incorporates a wide spectrum of physical models: different turbulence models, models for mass transfer accounting for chemical reactions and radioactive decay, several combustion models, a dispersed phase model, an electro-hydrodynamic model, an original VOF model for tracking moving interfaces. It should be noted that turbulence can be simulated within URANS, LES, and ILES approaches. FlowVision simulates fluid motion with velocities corresponding to all possible flow regimes: from incompressible to hypersonic. This is achieved by using an original all-speed velocity-pressure split algorithm for integration of the Navier-Stokes equations.

    FlowVision enables solving multi-physic problems with use of different modeling tools. For instance, one can simulate multi-phase flows with use of the VOF method, flows past bodies moving across a stationary grid (within Euler approach), flows in rotary machines with use of the technology of sliding grid. Besides that, the software solves fluid-structure interaction problems using the technology of two-way coupling of FlowVision with finite-element codes. Two examples of solving challenging problems in the FlowVision software are demonstrated in the given article. The first one is splashdown of a spacecraft after deceleration by means of jet engines. This problem is characterized by presence of moving bodies and contact surface between the air and the water in the computational domain. The supersonic jets interact with the air-water interphase. The second problem is simulation of the work of a human heart with artificial and natural valves designed on the basis of tomographic investigations with use of a finite-element model of the heart. This problem is characterized by two-way coupling between the “liquid” computational domain and the finite-element model of the hart muscles.

    Keywords: industrial computational fluid dynamics, gas dynamics, finite-volume method, Navier–Stokes equations, fluid-structure interaction.
    Views (last year): 30. Citations: 8 (RSCI).

• About Journal
• Open Access Policy
• Publishing Ethics
• Editorial board
• Author index
• For authors
• For Reviewers
• Contacts
• Most viewed papers
• Most cited papers
• Submit publication ONLINE