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  1. An approximate mathematical model of blood flow in an axisymmetric blood vessel is studied. Such a vessel is understood as an infinitely long circular cylinder, the walls of which consist of elastic rings. Blood is considered as an incompressible fluid flowing in this cylinder. Increased pressure causes radially symmetrical stretching of the elastic rings. Following J. Lamb, the rings are located close to each other so that liquid does not flow between them. To mentally realize this, it is enough to assume that the rings are covered with an impenetrable film that does not have elastic properties. Only rings have elasticity. The considered model of blood flow in a blood vessel consists of three equations: the continuity equation, the law of conservation of momentum and the equation of state. An approximate procedure for reducing the equations under consideration to the Korteweg – de Vries (KdV) equation is considered, which was not fully considered by J. Lamb, only to establish the dependence of the coefficients of the KdV equation on the physical parameters of the considered model of incompressible fluid flow in an axisymmetric vessel. From the KdV equation, by a standard transition to traveling waves, ODEs of the third, second and first orders are obtained, respectively. Depending on the different cases of arrangement of the three stationary solutions of the first-order ODE, a cnoidal wave and a soliton are standardly obtained. The main attention is paid to an unbounded periodic solution, which we call a degenerate cnoidal wave. Mathematically, cnoidal waves are described by elliptic integrals with parameters defining amplitudes and periods. Soliton and degenerate cnoidal wave are described by elementary functions. The hemodynamic meaning of these types of decisions is indicated. Due to the fact that the sets of solutions to first-, second- and third-order ODEs do not coincide, it has been established that the Cauchy problem for second- and third-order ODEs can be specified at all points, and for first-order ODEs only at points of growth or decrease. The Cauchy problem for a first-order ODE cannot be specified at extremum points due to the violation of the Lipschitz condition. The degeneration of the cnoidal wave into a degenerate cnoidal wave, which can lead to rupture of the vessel walls, is numerically illustrated. The table below describes two modes of approach of a cnoidal wave to a degenerate cnoidal wave.

  2. Gerasimov A.N., Shpitonkov M.I.
    Mathematical model of the parasite – host system with distributed immunity retention time
    Computer Research and Modeling, 2024, v. 16, no. 3, pp. 695-711

    The COVID-19 pandemic has caused increased interest in mathematical models of the epidemic process, since only statistical analysis of morbidity does not allow medium-term forecasting in a rapidly changing situation.

    Among the specific features of COVID-19 that need to be taken into account in mathematical models are the heterogeneity of the pathogen, repeated changes in the dominant variant of SARS-CoV-2, and the relative short duration of post-infectious immunity.

    In this regard, solutions to a system of differential equations for a SIR class model with a heterogeneous duration of post-infectious immunity were analytically studied, and numerical calculations were carried out for the dynamics of the system with an average duration of post-infectious immunity of the order of a year.

    For a SIR class model with a heterogeneous duration of post-infectious immunity, it was proven that any solution can be continued indefinitely in time in a positive direction without leaving the domain of definition of the system.

    For the contact number $R_0 \leqslant 1$, all solutions tend to a single trivial stationary solution with a zero share of infected people, and for $R_0 > 1$, in addition to the trivial solution, there is also a non-trivial stationary solution with non-zero shares of infected and susceptible people. The existence and uniqueness of a non-trivial stationary solution for $R_0 > 1$ was proven, and it was also proven that it is a global attractor.

    Also, for several variants of heterogeneity, the eigenvalues of the rate of exponential convergence of small deviations from a nontrivial stationary solution were calculated.

    It was found that for contact number values corresponding to COVID-19, the phase trajectory has the form of a twisting spiral with a period length of the order of a year.

    This corresponds to the real dynamics of the incidence of COVID-19, in which, after several months of increasing incidence, a period of falling begins. At the same time, a second wave of incidence of a smaller amplitude, as predicted by the model, was not observed, since during 2020–2023, approximately every six months, a new variant of SARS-CoV-2 appeared, which was more infectious than the previous one, as a result of which the new variant replaced the previous one and became dominant.

  3. Kondratyev M.A.
    Forecasting methods and models of disease spread
    Computer Research and Modeling, 2013, v. 5, no. 5, pp. 863-882

    The number of papers addressing the forecasting of the infectious disease morbidity is rapidly growing due to accumulation of available statistical data. This article surveys the major approaches for the shortterm and the long-term morbidity forecasting. Their limitations and the practical application possibilities are pointed out. The paper presents the conventional time series analysis methods — regression and autoregressive models; machine learning-based approaches — Bayesian networks and artificial neural networks; case-based reasoning; filtration-based techniques. The most known mathematical models of infectious diseases are mentioned: classical equation-based models (deterministic and stochastic), modern simulation models (network and agent-based).

    Views (last year): 71. Citations: 19 (RSCI).
  4. Kholodov A.S.
    About the Evolution of Perturbations Caused by the Movement of Meteoroids in the Earth’s Atmosphere
    Computer Research and Modeling, 2013, v. 5, no. 6, pp. 993-1030

    On the basis of the MGD equations we consider 2D- and 3D- nonstationary problems about the evolution of perturbations in the lower atmosphere and the Earth’s ionosphere which are caused by the movement of large meteoroids along gently sloping paths of the entry with the simulation of their destruction by the momentary increase of the midship at the point of the pressure head maximum. According to the results of our numerical investigation we obtain and analyze the detailed spatial-temporal distributions of the main parameters of the plasma flows from which in particular a number of phenomena that are similar to those seen in the Chelyabinsk phenomenon follow.

    Views (last year): 1. Citations: 1 (RSCI).
  5. Galitskii V.V.
    Sectional model of non-free tree growth
    Computer Research and Modeling, 2016, v. 8, no. 2, pp. 307-322

    The three-dimensional model of biomass dynamics of a tree growing on a limited territory presented. The tree consists of structural sections periodically arising on its top. Each section generates a virtual "tree". Adjacent virtual trees are nested each other and their difference is the section. Sections have biomass dynamics which differs from the dynamics of the tree and gradually die off (including in course of the free growth of the tree), giving effect denudation of trunk from bottom. This is observed in nature. The 3D-model of biomass dynamics of a tree, growing in a limited area, for describing the biomass dynamics of sections and their constituent sectors uses equations similar to those proposed earlier for the 2D-tree model. Examples of biomass dynamics of sectors, sections and tree obtained using the developed model are presented. The dynamics of the hodographs of the azimuthal biomass distribution of sections demonstrates that the lower sections of a tree growing in a limited area, are in oppression and die (more quickly compared with the model of freely growing tree), and new sections on top of the tree appear and grow freely. As a result, "wave" of tree biomass runs up the trunk.

    Views (last year): 1. Citations: 1 (RSCI).
  6. Davydov D.V., Shapoval A.B., Yamilov A.I.
    Languages in China provinces: quantitative estimation with incomplete data
    Computer Research and Modeling, 2016, v. 8, no. 4, pp. 707-716

    This paper formulates and solves a practical problem of data recovery regarding the distribution of languages on regional level in context of China. The necessity of this recovery is related to the problem of the determination of the linguistic diversity indices, which, in turn, are used to analyze empirically and to predict sources of social and economic development as well as to indicate potential conflicts at regional level. We use Ethnologue database and China census as the initial data sources. For every language spoken in China, the data contains (a) an estimate of China residents who claim this language to be their mother tongue, and (b) indicators of the presence of such residents in China provinces. For each pair language/province, we aim to estimate the number of the province inhabitants that claim the language to be their mother tongue. This base problem is reduced to solving an undetermined system of algebraic equations. Given additional restriction that Ethnologue database introduces data collected at different time moments because of gaps in Ethnologue language surveys and accompanying data collection expenses, we relate those data to a single time moment, that turns the initial task to an ’ill-posed’ system of algebraic equations with imprecisely determined right hand side. Therefore, we are looking for an approximate solution characterized by a minimal discrepancy of the system. Since some languages are much less distributed than the others, we minimize the weighted discrepancy, introducing weights that are inverse to the right hand side elements of the equations. This definition of discrepancy allows to recover the required variables. More than 92% of the recovered variables are robust to probabilistic modelling procedure for potential errors in initial data.

    Views (last year): 3.
  7. Shumov V.V.
    Consideration of psychological factors in models of the battle (conflict)
    Computer Research and Modeling, 2016, v. 8, no. 6, pp. 951-964

    The course and outcome of the battle is largely dependent on the morale of the troops, characterized by the percentage of loss in killed and wounded, in which the troops still continue to fight. Every fight is a psychological act of ending his rejection of one of the parties. Typically, models of battle psychological factor taken into account in the decision of Lanchester equations (the condition of equality of forces, when the number of one of the parties becomes zero). It is emphasized that the model Lanchester type satisfactorily describe the dynamics of the battle only in the initial stages. To resolve this contradiction is proposed to use a modification of Lanchester's equations, taking into account the fact that at any moment of the battle on the enemy firing not affected and did not abandon the battle fighters. The obtained differential equations are solved by numerical method and allow the dynamics to take into account the influence of psychological factor and evaluate the completion time of the conflict. Computational experiments confirm the known military theory is the fact that the fight usually ends in refusal of soldiers of one of the parties from its continuation (avoidance of combat in various forms). Along with models of temporal and spatial dynamics proposed to use a modification of the technology features of the conflict of S. Skaperdas, based on the principles of combat. To estimate the probability of victory of one side in the battle takes into account the interest of the maturing sides of the bloody casualties and increased military superiority.

    Views (last year): 7. Citations: 4 (RSCI).
  8. Galochkina T.V., Volpert V.A.
    Mathematical modeling of thrombin propagation during blood coagulation
    Computer Research and Modeling, 2017, v. 9, no. 3, pp. 469-486

    In case of vessel wall damage or contact of blood plasma with a foreign surface, the chain of chemical reactions called coagulation cascade is launched that leading to the formation of a fibrin clot. A key enzyme of the coagulation cascade is thrombin, which catalyzes formation of fibrin from fibrinogen. The distribution of thrombin concentration in blood plasma determines spatio-temporal dynamics of clot formation. Contact pathway of blood coagulation triggers the production of thrombin in response to the contact with a negatively charged surface. If the concentration of thrombin generated at this stage is large enough, further production of thrombin takes place due to positive feedback loops of the coagulation cascade. As a result, thrombin propagates in plasma cleaving fibrinogen that results in the clot formation. The concentration profile and the speed of propagation of thrombin are constant and do not depend on the type of the initial activator.

    Such behavior of the coagulation system is well described by the traveling wave solutions in a system of “reaction – diffusion” equations on the concentration of blood factors involved in the coagulation cascade. In this study, we carried out detailed analysis of the mathematical model describing the main reaction of the intrinsic pathway of coagulation cascade.We formulate necessary and sufficient conditions of the existence of the traveling wave solutions. For the considered model the existence of such solutions is equivalent to the existence of the wave solutions in the simplified one-equation model describing the dynamics of thrombin concentration derived under the quasi-stationary approximation.

    Simplified model also allows us to obtain analytical estimate of the thrombin propagation rate in the considered model. The speed of the traveling wave for one equation is estimated using the narrow reaction zone method and piecewise linear approximation. The resulting formulas give a good approximation of the velocity of propagation of thrombin in the simplified, as well as in the original model.

    Views (last year): 10. Citations: 1 (RSCI).
  9. Shokirov F.S.
    Interaction of a breather with a domain wall in a two-dimensional O(3) nonlinear sigma model
    Computer Research and Modeling, 2017, v. 9, no. 5, pp. 773-787

    By numerical simulation methods the interaction processes of oscillating soliton (breather) with a 180-degree Neel domain wall in the framework of a (2 + 1)-dimensional supersymmetric O(3) nonlinear sigma model is studied. The purpose of this paper is to investigate nonlinear evolution and stability of a system of interacting localized dynamic and topological solutions. To construct the interaction models, were used a stationary breather and domain wall solutions, where obtained in the framework of the two-dimensional sine-Gordon equation by adding specially selected perturbations to the A3-field vector in the isotopic space of the Bloch sphere. In the absence of an external magnetic field, nonlinear sigma models have formal Lorentz invariance, which allows constructing, in particular, moving solutions and analyses the experimental data of the nonlinear dynamics of an interacting solitons system. In this paper, based on the obtained moving localized solutions, models for incident and head-on collisions of breathers with a domain wall are constructed, where, depending on the dynamic parameters of the system, are observed the collisions and reflections of solitons from each other, a long-range interactions and also the decay of an oscillating soliton into linear perturbation waves. In contrast to the breather solution that has the dynamics of the internal degree of freedom, the energy integral of a topologically stable soliton in the all experiments the preserved with high accuracy. For each type of interaction, the range of values of the velocity of the colliding dynamic and topological solitons is determined as a function of the rotation frequency of the A3-field vector in the isotopic space. Numerical models are constructed on the basis of methods of the theory of finite difference schemes, using the properties of stereographic projection, taking into account the group-theoretical features of constructions of the O(N) class of nonlinear sigma models of field theory. On the perimeter of the two-dimensional modeling area, specially developed boundary conditions are established that absorb linear perturbation waves radiated by interacting soliton fields. Thus, the simulation of the interaction processes of localized solutions in an infinite two-dimensional phase space is carried out. A software module has been developed that allows to carry out a complex analysis of the evolution of interacting solutions of nonlinear sigma models of field theory, taking into account it’s group properties in a two-dimensional pseudo-Euclidean space. The analysis of isospin dynamics, as well the energy density and energy integral of a system of interacting dynamic and topological solitons is carried out.

    Views (last year): 6.
  10. Koroleva M.R., Mishenkova O.V., Raeder T., Tenenev V.A., Chernova A.A.
    Numerical simulation of the process of activation of the safety valve
    Computer Research and Modeling, 2018, v. 10, no. 4, pp. 495-509

    The conjugate problem of disk movement into gas-filled volume of the spring-type safety valve is solved. The questions of determining the physically correct value of the disk initial lift are considered. The review of existing approaches and methods for solving of such type problems is conducted. The formulation of the problem about the valve actuation when the vessel pressure rises and the mathematical model of the actuation processes are given. A special attention to the binding of physical subtasks is paid. Used methods, numerical schemes and algorithms are described. The mathematical modeling is performed on basе the fundamental system of differential equations for viscous gas movement with the equation for displacement of disk valve. The solution of this problem in the axe symmetric statement is carried out numerically using the finite volume method. The results obtained by the viscous and inviscid models are compared. In an inviscid formulation this problem is solved using the Godunov scheme, and in a viscous formulation is solved using the Kurganov – Tadmor method. The dependence of the disk displacement on time was obtained and compared with the experimental data. The pressure distribution on the disk surface, velocity profiles in the cross sections of the gap for different disk heights are given. It is shown that a value of initial drive lift it does not affect on the gas flow and valve movement part dynamic. It can significantly reduce the calculation time of the full cycle of valve work. Immediate isotahs for various elevations of the disk are presented. The comparison of jet flow over critical section is given. The data carried out by two numerical experiments are well correlated with each other. So, the inviscid model can be applied to the numerical modeling of the safety valve dynamic.

    Views (last year): 34. Citations: 1 (RSCI).
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