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The paper considers the adequacy of the model developed earlier by the author for the analysis of income inequality and based on an empirically confirmed hypothesis that the relative (to the income of the richest group) income values of 20% population groups in total income can be represented as a finite functional sequence, each member of which depends on one parameter — a specially defined indicator of inequality. It is shown that in addition to the existing methods of inequality analysis, the model makes it possible to estimate with the help of analytical expressions the income shares of 20%, 10% and smaller groups of the population for different levels of inequality, as well as to identify how they change with the growth of inequality, to estimate the level of inequality for known ratios between the incomes of different groups of the population, etc.

The paper provides a more detailed confirmation of the proposed model adequacy in comparison with the previously obtained results of statistical analysis of empirical data on the distribution of income between the 20% and 10% population groups. It is based on the analysis of certain ratios between the values of quintiles and deciles according to the proposed model. The verification of these ratios was carried out using a set of data for a large number of countries and the estimates obtained confirm the sufficiently high accuracy of the model.

Data are presented that confirm the possibility of using the model to analyze the dependence of income distribution by population groups on the level of inequality, as well as to estimate the inequality indicator for income ratios between different groups, including variants when the income of the richest 20% is equal to the income of the poor 60 %, income of the middle class 40% or income of the rest 80% of the population, as well as when the income of the richest 10% is equal to the income of the poor 40 %, 50% or 60%, to the income of various middle class groups, etc., as well as for cases, when the distribution of income obeys harmonic proportions and when the quintiles and deciles corresponding to the middle class reach a maximum. It is shown that the income shares of the richest middle class groups are relatively stable and have a maximum at certain levels of inequality.

The results obtained with the help of the model can be used to determine the standards for developing a policy of gradually increasing the level of progressive taxation in order to move to the level of inequality typical of countries with social oriented economy.

Laser polishing is a promising technology for the finishing of fused quartz (fused silica or quartz glass) products, enabling the removal of subsurface defects induced by mechanical processing. However, the complexity and nonlinearity of the physical processes occurring during laser irradiation complicate the selection of optimal technological parameters. The present paper aims to develop, comparatively analyze, and apply high-precision predictive models for forecasting and optimizing the key performance indicators of the laser polishing process for quartz glass. A verified finite element model implemented in the ANSYS software environment produced a dataset of temperature and stress fields for various combinations of process parameters. This dataset was used to develop and validate four types of predictive models: Polynomial Regression, a Fuzzy Logic System, an Adaptive Neuro-Fuzzy Inference System (ANFIS), and a Multilayer Perceptron (MLP) neural network. The models’ quality was evaluated on a test set using the statistical metrics MAE, RMSE, MAPE, $R^2$, and  $R^2_{Adj}$. A comparative analysis of the models revealed the significant superiority of the MLP neural network, which demonstrated the highest prediction accuracy for all output parameters, achieving Adjusted $R^2$ ($R^2_{Adj}$.) values above 0.97 and a Mean Absolute Percentage Error (MAPE) in the range of 0.7–2.8%. This model was effectively utilized as a surrogate function in combination with a genetic algorithm to successfully identify the optimal process parameters. The constructed MLP neural network model functions as a reliable and high-precision tool, facilitating both prediction and the optimization of fused quartz polishing outcomes using a CO₂ laser. This approach effectively approximates the complex nonlinear dependencies inherent in the process and can serve as a foundation for developing intelligent control and optimization systems for this technology.

The results of determination of the risk of cardiovascular failure of young athletes and adolescents in stressful physical activity have been demonstrated. The method of screening diagnostics of the risk of developing heart failure has been described. The results of contactless measurement of the form of the pulse wave of the radial artery using semiconductor laser autodyne have been presented. In the measurements used laser diode type RLD-650 specifications: output power of 5 mW, emission wavelength 654 nm. The problem was solved by the reduced form of the reflector movement, which acts as the surface of the skin of the human artery, tested method of assessing the risk of cardiovascular disease during exercise and the analysis of the results of its application to assess the risk of cardiovascular failure reactions of young athletes. As analyzed parameters were selected the following indicators: the steepness of the rise in the systolic portion of the fast and slow phase, the rate of change in the pulse wave catacrota variability of cardio intervals as determined by the time intervals between the peaks of the pulse wave. It analyzed pulse wave form on its first and second derivative with respect to time. The zeros of the first derivative of the pulse wave allow to set aside time in systolic rise. A minimum of the second derivative corresponds to the end of the phase and the beginning of the slow pressure build-up in the systole. Using the first and second derivative of the pulse wave made it possible to separately analyze the pulse wave form phase of rapid and slow pressure increase phase during systolic expansion. It has been established that the presence of anomalies in the form of the pulse wave in combination with vagotonic nervous regulation of the cardiovascular system of a patient is a sign of danger collapse of circulation during physical exercise.

The volume and structure of accumulated credit debt to the banking system depends on many factors, the most important of which is the level of interest rates. The correct assessment of borrowers’ reaction to the changes in the monetary policy allows to develop econometric models, representing the structure of the credit portfolio in the banking system by terms of lending. These models help to calculate indicators characterizing the level of interest rate risk in the whole system. In the study, we carried out the identification of four types of models: discrete linear model based on transfer functions; the state-space model; the classical econometric model ARMAX, and a nonlinear Hammerstein –Wiener model. To describe them, we employed the formal language of automatic control theory; to identify the model, we used the MATLAB software pack-age. The study revealed that the discrete linear state-space model is most suitable for short-term forecasting of both the volume and the structure of credit debt, which in turn allows to predict trends in the structure of accumulated credit debt on the forecasting horizon of 1 year. The model based on the real data has shown a high sensitivity of the structure of credit debt by pay back periods reaction to the changes in the Ñentral Bank monetary policy. Thus, a sharp increase in interest rates in response to external market shocks leads to shortening of credit terms by borrowers, at the same time the overall level of debt rises, primarily due to the increasing revaluation of nominal debt. During the stable falling trend of interest rates, the structure shifts toward long-term debts.

When person`s diseases is result of bacterial infection, various characteristics of the organism are used for observation the course of the disease. Currently, one of these indicators is dynamics of cytokine concentrations are produced, mainly by cells of the immune system. There are many types of these low molecular weight proteins in human body and many species of animals. The study of cytokines is important for the interpretation of functional disorders of the body's immune system, assessment of the severity, monitoring the effectiveness of therapy, predicting of the course and outcome of treatment. Cytokine response of the body indicating characteristics of course of disease. For research regularities of such indication, experiments were conducted on laboratory mice. Experimental data are analyzed on the development of pneumonia and treatment with several drugs for bacterial infection of mice. As drugs used immunomodulatory drugs “Roncoleukin”, “Leikinferon” and “Tinrostim”. The data are presented by two types cytokines` concentration in lung tissue and animal blood. Multy-sided statistical ana non statistical analysis of the data allowed us to find common patterns of changes in the “cytokine profile” of the body and to link them with the properties of therapeutic preparations. The studies cytokine “Interleukin-10” (IL-10) and “Interferon Gamma” (IFN$\gamma$) in infected mice deviate from the normal level of infact animals indicating the development of the disease. Changes in cytokine concentrations in groups of treated mice are compared with those in a group of healthy (not infected) mice and a group of infected untreated mice. The comparison is made for groups of individuals, since the concentrations of cytokines are individual and differ significantly in different individuals. Under these conditions, only groups of individuals can indicate the regularities of the processes of the course of the disease. These groups of mice were being observed for two weeks. The dynamics of cytokine concentrations indicates characteristics of the disease course and efficiency of used therapeutic drugs. The effect of a medicinal product on organisms is monitored by the location of these groups of individuals in the space of cytokine concentrations. The Hausdorff distance between the sets of vectors of cytokine concentrations of individuals is used in this space. This is based on the Euclidean distance between the elements of these sets. It was found that the drug “Roncoleukin” and “Leukinferon” have a generally similar and different from the drug “Tinrostim” effect on the course of the disease.

The article substantiates the need to develop and analyze mathematical models that take into account the mutual influence of long (Kondratiev) waves of economic development. The analysis of the available publications shows that at the model level, the direct and inverse relationships between intersecting long waves are still insufficiently studied. As practice shows, the production of the current long wave can receive an additional impetus for growth from the technologies of the next long wave. The technologies of the next industrial revolution often serve as improving innovations for the industries born of the previous industrial revolution. As a result, the new long wave increases the amplitude of the oscillations of the trajectory of the previous long wave. Such results of the interaction of long waves in the economy are similar to the effects of interference of physical waves. The mutual influence of the recessions and booms of the economies of different countries gives even more grounds for comparing the consequences of this mutual influence with the interference of physical waves. The article presents a model for the development of the technological base of production, taking into account the possibilities of combining old and new technologies. The model consists of several sub-models. The use of a different mathematical description for the individual stages of updating the technological base of production allows us to take into account the significant differences between the successive phases of the life cycle of general purpose technologies, considered in modern literature as the technological basis of industrial revolutions. One of these phases is the period of formation of the appropriate infrastructure necessary for the intensive diffusion of new general purpose technology, for the rapid development of industries using this technology. The model is used for illustrative calculations with the values of exogenous parameters corresponding to the logic of changing long waves. Despite all the conditionality of the illustrative calculations, the configuration of the curve representing the change in the return on capital in the simulated period is close to the configuration of the real trajectory of the return on private fixed assets of the US economy in the period 1982-2019. The factors that remained outside the scope of the presented model, but which are advisable to take into account when describing the interference of long waves of economic development, are indicated.

Social media is a crucial indicator of the position of assets in the financial market. The paper describes the rigid solution for the classification problem to determine the influence of social media activity on financial market movements. Reputable crypto traders influencers are selected. Twitter posts packages are used as data. The methods of text, which are characterized by the numerous use of slang words and abbreviations, and preprocessing consist in lemmatization of Stanza and the use of regular expressions. A word is considered as an element of a vector of a data unit in the course of solving the problem of binary classification. The best markup parameters for processing Binance candles are searched for. Methods of feature selection, which is necessary for a precise description of text data and the subsequent process of establishing dependence, are represented by machine learning and statistical analysis. First, the feature selection is used based on the information criterion. This approach is implemented in a random forest model and is relevant for the task of feature selection for splitting nodes in a decision tree. The second one is based on the rigid compilation of a binary vector during a rough check of the presence or absence of a word in the package and counting the sum of the elements of this vector. Then a decision is made depending on the superiority of this sum over the threshold value that is predetermined previously by analyzing the frequency distribution of mentions of the word. The algorithm used to solve the problem was named benchmark and analyzed as a tool. Similar algorithms are often used in automated trading strategies. In the course of the study, observations of the influence of frequently occurring words, which are used as a basis of dimension 2 and 3 in vectorization, are described as well.

The dynamics of various gaseous substances is of great importance in the vital activity of phytoplankton. The dynamics of oxygen and carbon dioxide are the most indicative for aquatic plant communities. These dynamics are important for the global ratio of oxygen and carbon dioxide in the Earth’s atmosphere. The goal of the work is to use the mathematical modeling to study the role of oxygen and carbon dioxide in the life of aquatic plant organisms, in particular, the phytoplankton. The series of mathematical models of the dynamics of oxygen and carbon dioxide in the phytoplankton body are proposed. The series of models are built according to the increasing degree of complexity and the number of modeled processes. At first, the simplest model of only gas dynamics is considered, then there is a transition to models with the interaction and mutual influence of gases on the formation and dynamics of energy-intensive substances and on growth processes in the plant organism. Photosynthesis and respiration are considered as the basis of the models. The models study the properties of solutions: equilibrium solutions and their stability, dynamic properties of solutions. Various types of equilibrium stability, possible complex non-linear dynamics have been identified. These properties allow better orientation when choosing a model to describe processes with a known set of data and formulated modeling goals. An example of comparing an experiment with its model description is given. The next goal of modeling — to link gas dynamics for oxygen and carbon dioxide with metabolic processes in plant organisms. In the future, model designs will be applied to the analysis of ecosystem behavior when the habitat changes, including the content of gaseous substances.

Analysis of regional economic indicators plays a crucial role in management and development planning, with Gross Regional Product (GRP) serving as one of the key indicators of economic activity. The application of artificial intelligence, including neural network technologies, enables significant improvements in the accuracy and reliability of forecasts of economic processes. This study compares three neural network algorithm models for predicting the GRP of a typical region of the Russian Federation — the Udmurt Republic — based on time series data from 2000 to 2023. The selected models include a neural network with the Bat Algorithm (BA-LSTM), a neural network model based on backpropagation error optimized with a Genetic Algorithm (GA-BPNN), and a neural network model of Elman optimized using the Particle Swarm Optimization algorithm (PSO-Elman). The research involved stages of neural network modeling such as data preprocessing, training model, and comparative analysis based on accuracy and forecast quality metrics. This approach allows for evaluating the advantages and limitations of each model in the context of GRP forecasting, as well as identifying the most promising directions for further research. The utilization of modern neural network methods opens new opportunities for automating regional economic analysis and improving the quality of forecast assessments, which is especially relevant when data are limited and for rapid decision-making. The study uses factors such as the amount of production capital, the average annual number of labor resources, the share of high-tech and knowledge-intensive industries in GRP, and an inflation indicator as input data for predicting GRP. The high accuracy of the predictions achieved by including these factors in the neural network models confirms the strong correlation between these factors and GRP. The results demonstrate the exceptional accuracy of the BA-LSTM neural network model on validation data: the coefficient of determination was 0.82, and the mean absolute percentage error was 4.19%. The high performance and reliability of this model confirm its capacity to predict effectively the dynamics of the GRP. During the forecast period up to 2030, the Udmurt Republic is expected to experience an annual increase in Gross Regional Product (GRP) of +4.6% in current prices or +2.5% in comparable 2023 prices. By 2030, the GRP is projected to reach 1264.5 billion rubles.

Acute respiratory infections are a major public health concern because they are the leading cause of illness and death in many countries. Therefore, there is great interest in developing models and methods capable of modeling the spread of these infections within communities, with the aim of controlling outbreaks and preventing their spread. Agent-based models (ABM) are one of the most important tools in epidemiological research for modeling epidemic dynamics in realistic populations, but they face significant challenges in terms of computational complexity in their operation and calibration of epidemiological data, as parameter estimation typically requires repeated simulations across large parameter spaces to determine plausible values for key epidemiological parameters. This paper addresses the problem of alleviating computational constraints in the inverse problem of calibrating an ABM model for simulating the spread of respiratory infections in Saint Petersburg. The paper proposes the application of machine learning surrogate to link epidemic trajectories to underlying epidemiological parameters, enabling them to quickly infer parameter estimates from observed epidemic data. This is done by formulating the task of calibrating ABMs against epidemiological data as a supervised learning problem, where sequences extracted from epidemiological trajectories are associated with underlying epidemiological parameters. The research was based on evaluating the performance of attention-based sequence modeling, probabilistic deep learning, and distributional regression for inferring parameter estimates from truncated sequences of epidemic trajectories. Experimental evaluations have demonstrated the effectiveness of this approach and its practical and straightforward application. The results also indicated the superiority of attention-based sequence modeling, as it showed more consistent performance across metrics and horizons in accurate parameter estimation and credible uncertainty quantification. Distributional regression modeling also showed good performance with specific strengths in point accuracy while probabilistic deep learning performed poorly, especially at longer input horizons.